PET demonstrates reduced dopamine transporter expression in PD with dyskinesias.
Identifieur interne : 001E02 ( Main/Exploration ); précédent : 001E01; suivant : 001E03PET demonstrates reduced dopamine transporter expression in PD with dyskinesias.
Auteurs : A R Troiano [Canada] ; R. De La Fuente-Fernandez ; V. Sossi ; M. Schulzer ; E. Mak ; T J Ruth ; A J StoesslSource :
- Neurology [ 1526-632X ] ; 2009.
English descriptors
- KwdEn :
- Caudate Nucleus (diagnostic imaging), Caudate Nucleus (metabolism), Dopamine Plasma Membrane Transport Proteins (biosynthesis), Dopamine Plasma Membrane Transport Proteins (genetics), Dyskinesias (diagnostic imaging), Dyskinesias (metabolism), Female, Humans, Logistic Models, Male, Methylphenidate, Middle Aged, Parkinson Disease (diagnostic imaging), Parkinson Disease (metabolism), Positron-Emission Tomography, Putamen (diagnostic imaging), Putamen (metabolism), Radiopharmaceuticals, Tetrabenazine (analogs & derivatives).
- MESH :
- chemical , analogs & derivatives : Tetrabenazine.
- chemical , biosynthesis : Dopamine Plasma Membrane Transport Proteins.
- diagnostic imaging : Caudate Nucleus, Dyskinesias, Parkinson Disease, Putamen.
- chemical , genetics : Dopamine Plasma Membrane Transport Proteins.
- metabolism : Caudate Nucleus, Dyskinesias, Parkinson Disease, Putamen.
- Female, Humans, Logistic Models, Male, Methylphenidate, Middle Aged, Positron-Emission Tomography, Radiopharmaceuticals.
Abstract
Dyskinesias are common in Parkinson disease (PD). Prior investigations suggest that dopamine (DA) terminals compensate for abnormal DA transmission. We verified whether similar adaptations could be related to the development of treatment-related complications.
DOI: 10.1212/01.wnl.0000338631.73211.56
PubMed: 19020294
Affiliations:
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Le document en format XML
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Sossi</name></author><author><name sortKey="Schulzer, M" sort="Schulzer, M" uniqKey="Schulzer M" first="M" last="Schulzer">M. Schulzer</name></author><author><name sortKey="Mak, E" sort="Mak, E" uniqKey="Mak E" first="E" last="Mak">E. Mak</name></author><author><name sortKey="Ruth, T J" sort="Ruth, T J" uniqKey="Ruth T" first="T J" last="Ruth">T J Ruth</name></author><author><name sortKey="Stoessl, A J" sort="Stoessl, A J" uniqKey="Stoessl A" first="A J" last="Stoessl">A J Stoessl</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2009">2009</date><idno type="RBID">pubmed:19020294</idno><idno type="pmid">19020294</idno><idno type="doi">10.1212/01.wnl.0000338631.73211.56</idno><idno type="wicri:Area/PubMed/Corpus">000E83</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000E83</idno><idno type="wicri:Area/PubMed/Curation">000E83</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000E83</idno><idno type="wicri:Area/PubMed/Checkpoint">000E83</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000E83</idno><idno type="wicri:Area/Ncbi/Merge">000986</idno><idno type="wicri:Area/Ncbi/Curation">000986</idno><idno type="wicri:Area/Ncbi/Checkpoint">000986</idno><idno type="wicri:Area/Main/Merge">001F50</idno><idno type="wicri:Area/Main/Curation">001E02</idno><idno type="wicri:Area/Main/Exploration">001E02</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">PET demonstrates reduced dopamine transporter expression in PD with dyskinesias.</title><author><name sortKey="Troiano, A R" sort="Troiano, A R" uniqKey="Troiano A" first="A R" last="Troiano">A R Troiano</name><affiliation wicri:level="1"><nlm:affiliation>Pacific Parkinson's Research Centre, Vancouver, BC, Canada. andretroiano@gmail.com</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Pacific Parkinson's Research Centre, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="De La Fuente Fernandez, R" sort="De La Fuente Fernandez, R" uniqKey="De La Fuente Fernandez R" first="R" last="De La Fuente-Fernandez">R. De La Fuente-Fernandez</name></author><author><name sortKey="Sossi, V" sort="Sossi, V" uniqKey="Sossi V" first="V" last="Sossi">V. Sossi</name></author><author><name sortKey="Schulzer, M" sort="Schulzer, M" uniqKey="Schulzer M" first="M" last="Schulzer">M. Schulzer</name></author><author><name sortKey="Mak, E" sort="Mak, E" uniqKey="Mak E" first="E" last="Mak">E. Mak</name></author><author><name sortKey="Ruth, T J" sort="Ruth, T J" uniqKey="Ruth T" first="T J" last="Ruth">T J Ruth</name></author><author><name sortKey="Stoessl, A J" sort="Stoessl, A J" uniqKey="Stoessl A" first="A J" last="Stoessl">A J Stoessl</name></author></analytic><series><title level="j">Neurology</title><idno type="eISSN">1526-632X</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Caudate Nucleus (diagnostic imaging)</term><term>Caudate Nucleus (metabolism)</term><term>Dopamine Plasma Membrane Transport Proteins (biosynthesis)</term><term>Dopamine Plasma Membrane Transport Proteins (genetics)</term><term>Dyskinesias (diagnostic imaging)</term><term>Dyskinesias (metabolism)</term><term>Female</term><term>Humans</term><term>Logistic Models</term><term>Male</term><term>Methylphenidate</term><term>Middle Aged</term><term>Parkinson Disease (diagnostic imaging)</term><term>Parkinson Disease (metabolism)</term><term>Positron-Emission Tomography</term><term>Putamen (diagnostic imaging)</term><term>Putamen (metabolism)</term><term>Radiopharmaceuticals</term><term>Tetrabenazine (analogs & derivatives)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Tetrabenazine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Dopamine Plasma Membrane Transport Proteins</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Caudate Nucleus</term><term>Dyskinesias</term><term>Parkinson Disease</term><term>Putamen</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Dopamine Plasma Membrane Transport Proteins</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Caudate Nucleus</term><term>Dyskinesias</term><term>Parkinson Disease</term><term>Putamen</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Humans</term><term>Logistic Models</term><term>Male</term><term>Methylphenidate</term><term>Middle Aged</term><term>Positron-Emission Tomography</term><term>Radiopharmaceuticals</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Dyskinesias are common in Parkinson disease (PD). Prior investigations suggest that dopamine (DA) terminals compensate for abnormal DA transmission. We verified whether similar adaptations could be related to the development of treatment-related complications.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><noCountry><name sortKey="De La Fuente Fernandez, R" sort="De La Fuente Fernandez, R" uniqKey="De La Fuente Fernandez R" first="R" last="De La Fuente-Fernandez">R. De La Fuente-Fernandez</name><name sortKey="Mak, E" sort="Mak, E" uniqKey="Mak E" first="E" last="Mak">E. Mak</name><name sortKey="Ruth, T J" sort="Ruth, T J" uniqKey="Ruth T" first="T J" last="Ruth">T J Ruth</name><name sortKey="Schulzer, M" sort="Schulzer, M" uniqKey="Schulzer M" first="M" last="Schulzer">M. Schulzer</name><name sortKey="Sossi, V" sort="Sossi, V" uniqKey="Sossi V" first="V" last="Sossi">V. Sossi</name><name sortKey="Stoessl, A J" sort="Stoessl, A J" uniqKey="Stoessl A" first="A J" last="Stoessl">A J Stoessl</name></noCountry><country name="Canada"><noRegion><name sortKey="Troiano, A R" sort="Troiano, A R" uniqKey="Troiano A" first="A R" last="Troiano">A R Troiano</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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